TMDE, operating in its industry, demonstrates permissible primary business activities in medical technology focused on organ preservation and transport. However, the company's financial structure, characterized by an exceptionally high debt ratio of 397.26%, results in non-compliance across major Shariah screening standards. Income sources are clean with only 0.37% interest income requiring minimal purification. Despite low ESG risks and no controversies impacting compliance, the stock is excluded from all major Shariah indices due to debt concerns. Investors should monitor debt reduction efforts for potential future compliance.