Avidity Biosciences, Inc. (RNA), a biotechnology company developing innovative therapies for rare neuromuscular diseases, exhibits strong alignment with Shariah principles. Its core business promotes the preservation of life through ethical medical research, with no involvement in prohibited activities. Financial ratios significantly outperform industry benchmarks and all major thresholds, indicating robust compliance. While not included in all indices due to its small-cap status, inclusion in key Shariah indices confirms overall acceptability. Investors may proceed with minimal purification requirements.