The Amplify Seymour Cannabis ETF (CNBS) is an actively managed fund providing exposure to the U.S. cannabis ecosystem. This report assesses its Shariah compliance across financial, business activity, ESG, and multi-perspective criteria. Due to its investment in cannabis-related businesses, classified as non-permissible under Islamic principles (intoxicants), CNBS fails core business activity screening. Financial ratios are unassessable due to ETF structure, but index exclusions confirm non-compliance. Investors should avoid or seek scholarly guidance for any medical cannabis nuances.